This will be the 15th consecutive year in which the International Symposium on Hepatitis C Virus and Related Viruses has been held. Over the past decade, this symposium has become the premier venue for the presentation of breakthrough scientific discoveries in the field of hepatitis C. Last held in Glasgow, Scotland in September, 2007, the meeting attracted 930 delegates from all over the world. There were well over 300 oral and poster presentations, representing the cutting edge of hepatitis C research. We anticipate even greater attendance and many new scientific advances to be reported next fall in San Antonio. We look forward to seeing you at the 15th International Symposium on Hepatitis C Virus and Related Viruses!